'Sciatica' (pain referring down the leg) can often come from the sacroiliac ligaments.
Prolotherapy, also known as regenerative injection therapy, involves the local injection of a glucose solution into stretched, weak and damaged ligaments or tendons. The glucose acts as an irritant to the ligament, or tendon to induce local inflammation (the 1st phase of healing!), with the subsequent phases of healing occurring over a 4 - 6 week period following the injection - resulting in its strengthening and tightening.
Ankle sprains are a very common & problematic injury example, with an often systemic (whole body) effect on the musculo-skeletal system.
Other typical symptoms that can benefit from prolotherapy include muscle weakness & tightness, joints that crack, pop, grind, click or crunch, along with unstable joints.
Intra-articular (inside the joint) injections can also be done.
Muscles which are frequently tight, and have trigger points, are often the result of a ligament that is too loose, resulting in the muscle/s around the joint having to work harder (as a muscle & a 'ligament') in an attempt to stabilise the joint, which can lead to symptoms such as tendonitis.
It's also interesting to note that ligaments themselves have referral patterns to other areas of the body (just like muscle trigger points).
Prolotherapy appointments are usually no longer than 15mins in length, however an initial musculo-skeletal assessment is required to determine the best application of the injections. 1 - 6 treatments may be necessary depending on a patient's individual case, and response to the prolotherapy.